Hydroxyapatite Powder (Purity: 99.5+, Size: 40-50 µm)
Technical Specifications:
- Material: Hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂)
- Purity: 99.5% or higher
- Particle Size: 40-50 µm (microns)
- Shape: Typically irregular or spherical, depending on the manufacturing process
- Density: Approximately 3.1 g/cm³
- Melting Point: Decomposes at high temperatures (>1,100°C)
- Boiling Point: Decomposes before boiling
- Chemical Composition:
- Calcium (Ca): ~39%
- Phosphorus (P): ~18%
- Oxygen (O): ~43%
- Hydroxyl group (OH): Present in the structure
Applications:
- Bone Substitutes and Grafting:
- Hydroxyapatite is widely used in bone grafting materials due to its biocompatibility and similarity to the mineral component of human bones. The 40-50 µm particle size is ideal for creating bone substitutes and grafts that can aid in bone regeneration and healing. It is commonly used in orthopedic surgery and dental implants to repair bone defects and promote osseointegration (the process by which bone grows into the implant surface).
- It is used to treat fractures, bone diseases, and for dental implant procedures such as bone augmentation.
- Dental Applications:
- Hydroxyapatite powder is commonly used in dentistry for applications such as dental implants, fillings, coatings, and bonding agents. The 40-50 µm powder size is ideal for producing dental cements and adhesives that promote bone integration with titanium or other materials used in dental implants.
- HAp powder is also used in toothpaste formulations to remineralize teeth, reduce sensitivity, and repair enamel.
- Bone Tissue Engineering:
- Hydroxyapatite is used in bone tissue engineering as a scaffold material to support the growth of bone cells. The micron-sized particles allow for improved cell adhesion and growth, making it suitable for creating biodegradable scaffolds that help regenerate bone tissue. These scaffolds serve as temporary structures that facilitate bone formation before being resorbed by the body.
- HAp is combined with other biocompatible materials like collagen, polymers, or composite materials for bone repair and regeneration.
- Orthopedic Implants:
- Hydroxyapatite is often used as a coating for orthopedic implants such as hip replacements, knee implants, and spinal implants. The micron powder is typically applied to implants made of titanium or stainless steel to enhance osseointegration and improve the biological compatibility of the implant. The coating promotes bone growth on the implant’s surface, improving implant stability and long-term performance.
- The 40-50 µm size ensures that the coating provides optimal biomechanical properties and integration with natural bone.
- Drug Delivery Systems:
- Hydroxyapatite is used as a drug delivery carrier due to its high surface area and biocompatibility. It is ideal for use in controlled release systems, where drugs are delivered locally over a period of time. The micron powder can absorb and release a variety of therapeutic agents, including anti-cancer drugs, antibiotics, and anti-inflammatory agents, in a targeted and controlled manner.
- It is often employed in bone-targeting drug delivery systems, where the material is used to deliver drugs directly to bone tissues affected by bone diseases like osteoporosis and bone cancer.
- Wound Healing:
- Hydroxyapatite is used in wound healing applications due to its osteoconductivity, meaning it helps promote bone formation at wound sites. It is incorporated into wound dressings, bandages, and topical gels for bone-related wounds or bone fractures.
- It is also useful in treating chronic wounds, diabetic ulcers, and bone-related wounds to promote faster healing and bone regeneration.
- Radiology and Imaging:
- Hydroxyapatite is used as a contrast agent in medical imaging, especially in X-rays and CT scans for bone imaging. Due to its similarity to natural bone, HAp powder helps improve the visibility and definition of bone structures in imaging studies, providing clearer diagnostic images for bone-related conditions.
- It is also used in radiopharmaceuticals for detecting bone metastasis and bone-related diseases such as osteoporosis and osteosarcoma.
- Cosmetic and Skin Care Products:
- Hydroxyapatite is used in cosmetics and skincare products due to its remineralizing and hydrating properties. It is incorporated into creams, serums, and facial masks to help repair skin, promote regeneration, and boost hydration. The 40-50 µm powder is especially beneficial in the formulation of skin-rejuvenating products that provide moisture and reduce skin aging effects.
- It is also used in anti-aging creams, facial serums, and skin toners to enhance skin cell regeneration and strengthen the skin’s natural barrier.
- Bone Cement:
- Hydroxyapatite is used in the formulation of bone cement, particularly in orthopedic surgeries such as joint replacement and spinal surgery. The micron powder is mixed with polymer resins to form a biocompatible cement that provides strong adhesion between prosthetic implants and bone tissue.
- The cement helps stabilize implants during healing and improves the long-term stability of the implant.
- Research and Development:
- Hydroxyapatite micron powder is widely used in research and development for studying new applications in bone regeneration, drug delivery, and tissue engineering. Researchers use HAp to explore novel biomaterials, composite materials, and stem cell therapies for the treatment of bone diseases and bone defects.
- It is also used to test biocompatibility and osteointegration properties in pre-clinical and clinical trials for bone-related therapies.
Hydroxyapatite Powder (Purity: 99.5+, Size: 40-50 µm) is a biocompatible and osteoconductive material that plays a key role in bone regeneration, dental applications, drug delivery, and biomedical implants. The micron powder ensures high surface area for cell adhesion and growth, making it ideal for use in bone grafts, orthopedic implants, dental procedures, and wound healing. Its biocompatibility, biodegradability, and chemical similarity to bone make it indispensable for tissue engineering and regenerative medicine.
