Hydroxyapatite Powder (Purity: 99.5+, Size: 10-20 µm)
Technical Specifications:
- Material: Hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂)
- Purity: 99.5% or higher
- Particle Size: 10-20 µm (microns)
- Shape: Typically spherical or irregular, depending on the manufacturing process
- Density: Approximately 3.1 g/cm³
- Melting Point: Does not melt, decomposes at high temperatures (>1,100°C)
- Boiling Point: Decomposes before boiling
- Chemical Composition:
- Calcium (Ca): ~39%
- Phosphorus (P): ~18%
- Oxygen (O): ~43%
- Hydroxyl group (OH): Present in the structure
Applications:
- Bone Grafting and Regeneration:
- Hydroxyapatite is widely used in bone grafting materials due to its biocompatibility and similarity to the mineral component of human bones. The micron powder form is incorporated into bone grafts and implants to aid in bone regeneration and healing.
- It is used in the development of bone substitutes, scaffolds, and implants for treating bone defects, fractures, and bone loss in orthopedic surgery.
- Dental Applications:
- Hydroxyapatite powder is used in dentistry to manufacture dental implants, fillings, and coatings. The micron powder is used in dental cements and adhesives, as well as in toothpastes to help repair enamel and promote remineralization.
- Hydroxyapatite’s ability to mimic the natural composition of tooth enamel and bone makes it a crucial material in restorative dentistry.
- Bone Tissue Engineering:
- Hydroxyapatite is used in bone tissue engineering as a scaffold material. The micron powder is incorporated into biodegradable scaffolds that provide support for bone cell growth and tissue regeneration. The high surface area of the powder helps support cell attachment and proliferation, making it essential for cell-based regenerative therapies.
- It is commonly used in 3D printing to create customized scaffolds for patients needing personalized bone treatments.
- Orthopedic Implants:
- Hydroxyapatite is often used in the coating of orthopedic implants, such as joint replacements and spinal implants, to improve osseointegration (the process by which bone fuses to the implant). The micron powder is applied as a coating on implants made of titanium or stainless steel to enhance the implant’s biological compatibility and bone integration.
- This helps to improve implant stability and reduce rejection rates in orthopedic surgeries.
- Drug Delivery Systems:
- Hydroxyapatite is used as a drug delivery carrier for biocompatible and targeted delivery in medical treatments. Its high surface area and ability to absorb a wide variety of therapeutic agents make it ideal for use in controlled drug release and local drug delivery systems.
- The micron powder is used in nanoparticle formulations for cancer therapies, bone disease treatments, and anti-inflammatory drugs.
- Wound Healing:
- Hydroxyapatite is used in wound healing applications due to its osteoconductivity, meaning it promotes bone growth in wound areas. HAp powder is applied in wound dressings, bandages, and topical gels to accelerate healing and promote tissue regeneration.
- It is particularly useful in treating chronic wounds, diabetic ulcers, and bone-related wounds.
- Cosmetic and Skin Care Products:
- Hydroxyapatite is used in cosmetic and skincare products for its remineralizing and skin-repairing properties. It is added to creams, serums, and facial masks as a moisturizer and skin revitalizer.
- The micron powder is used in cosmetic formulations to promote cell regeneration, reduce skin aging, and boost hydration.
- Radiology and Imaging:
- Hydroxyapatite is used as a contrast agent in medical imaging. Due to its similarity to bone and radiopacity, HAp powder is used in X-ray and CT imaging for bone imaging and diagnostic procedures.
- It is also used in radiopharmaceuticals to assist in the detection of bone disorders and metastases in cancer patients.
- Bone Cement:
- Hydroxyapatite is used in the formulation of bone cement used in orthopedic surgeries to anchor implants in the bone. The micron powder is mixed with polymer resins to form a biocompatible cement that provides structural support and helps in faster healing after joint replacement surgeries.
- HAp-based bone cements are increasingly preferred due to their similarity to natural bone and their ability to integrate with the surrounding bone tissue.
- Research and Development:
- Hydroxyapatite micron powder is used in research and development for exploring new applications in bone tissue engineering, drug delivery systems, and medical implants. Researchers use HAp to study the biological interaction between bone and implant materials, nanomaterial development, and the growth and differentiation of stem cells for bone regeneration.
- It is also used in biomaterial testing, biocompatibility studies, and the development of next-generation bone-related medical devices.
Hydroxyapatite Powder (Purity: 99.5+, Size: 10-20 µm) is a versatile biomaterial that is widely used in bone regeneration, dental applications, drug delivery systems, and medical implants due to its biocompatibility, osteoconductivity, and bone-like properties. The micron powder form ensures high surface area, allowing for improved cell adhesion, growth, and integration with bone tissue, making it a critical material for bone repair, orthopedic implants, and cosmetic applications. Its extensive use in wound healing, radiology, and research highlights its importance in both clinical and research settings, driving advances in regenerative medicine, biomaterials, and bone-related therapies.
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